코디세핀 건강과 웰빙을 위한: 곤충병원성 Cordyceps 약용 곰팡이의 강력한 생체 활성 대사산물 및 그 기능식품 및 치료 잠재력.

한국어 요약

2020년 발표된 「Cordycepin for Health and Wellbeing: A Potent Bioactive Metabolite of an Entomopathogenic Cordyceps Medicinal Fungus and Its Nutraceutical and Therapeutic Potential.」은(는) 균종 미특정 및 코디세핀 관련 서술적 리뷰입니다. 아래는 원문 초록을 바탕으로 한 중립적 요약이며, 제품 효능·효과를 의미하지 않습니다.

초록 요지

Cordyceps is a rare naturally occurring entomopathogenic fungus usually found at high altitudes on the Himalayan plateau and a well-known medicinal mushroom in traditional Chinese medicine. Cordyceps contains various bioactive components, out of which, cordycepin is considered most vital, due to its utmost therapeutic as well as nutraceutical potential. Moreover, the structure similarity of cordycepin with adenosine makes it an important bioactive component, with difference of only hydroxyl group, lacking in the 3' position of its ribose moiety. Cordycepin is known for various nutraceutical and therapeutic potential, such as anti-diabetic, anti-hyperlipidemia, anti-fungal, anti-inflammatory, immunomodulatory, antioxidant, anti-aging, anticancer, antiviral, hepato-protective, hypo-sexuality, cardiovascular diseases, antimalarial, anti-osteoporotic, anti-arthritic, cosmeceutical etc. which makes it a most valuable medicinal mushroom for helping in maintaining good health. In this review, effort has been made to bring altogether the possible wide range of cordycepin's nutraceutical potential along with its pharmacological actions and possible mechanism. Additionally, it also summarizes the details of cordycepin based nutraceuticals predominantly available in the market with expected global value. Moreover, this review will attract the attention of food scientists, nutritionists, pharmaceutical and food industries to improve the use of bioactive molecule cordycepin for nutraceutical purposes with commercialization to aid and promote healthy lifestyle, wellness and wellbeing.

전문가 메모

• 연구 수준: 리뷰·고찰 · 서술적 리뷰
• 대상: 균종 미특정 / cordycepin
• 제품 연관성: partial
• 해석 주의: 원문에 질병·치료 관련 서술이 포함되어 있습니다. 본 요약은 성분·균류 연구 맥락만 중립적으로 정리했습니다.
• 인사이트: 여러 연구를 종합한 고찰이므로, 개별 실험의 질·편향을 원문 표/부록에서 확인하는 것이 좋습니다.

출처 · 원문

• 제목: Cordycepin for Health and Wellbeing: A Potent Bioactive Metabolite of an Entomopathogenic Cordyceps Medicinal Fungus and Its Nutraceutical and Therapeutic Potential.
• 저자: Syed Amir Ashraf 외 8명
• 연도: 2020
• 저널: Molecules (Basel, Switzerland)
• DOI: 10.3390/molecules24122231
• PMID: 32545666
• 링크: https://pubmed.ncbi.nlm.nih.gov/32545666/

원문 초록 (English)

Summary — Cordyceps is a rare naturally occurring entomopathogenic fungus usually found at high altitudes on the Himalayan plateau and a well-known medicinal mushroom in traditional Chinese medicine. Cordyceps contains various bioactive components, out of which, cordycepin is considered most vital, due to its utmost therapeutic as well as nutraceutical potential. Moreover, the structure similarity of cordycepin with adenosine makes it an important bioactive component, with difference of only hydroxyl group, lacking in the 3' position of its ribose moiety. Cordycepin is known for various nutraceutical and therapeutic potential, such as anti-diabetic, anti-hyperlipidemia, anti-fungal, anti-inflammatory, immunomodulatory, antioxidant, anti-aging, anticancer, antiviral, hepato-protective, hypo-sexuality, cardiovascular diseases, antimalarial, anti-osteoporotic, anti-arthritic, cosmeceutical etc. which makes it a most valuable medicinal mushroom for helping in maintaining good health. In this review, effort has been made to bring altogether the possible wide range of cordycepin's nutraceutical potential along with its pharmacological actions and possible mechanism. Additionally, it also summarizes the details of cordycepin based nutraceuticals predominantly available in the market with expected global value. Moreover, this review will attract the attention of food scientists, nutritionists, pharmaceutical and food industries to improve the use of bioactive molecule cordycepin for nutraceutical purposes with commercialization to aid and promote healthy lifestyle, wellness and wellbeing.

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본 페이지는 학술 문헌을 연구·교육 목적으로 요약·정리한 자료입니다. 질병의 예방·치료·진단과 무관하며, 제왕충초 담금주의 효능·효과를 주장하지 않습니다. ‘효능 관련 논문’은 연구자들이 다루는 생리활성·기능성 주제를 뜻하며, 제품 광고 문구가 아닙니다. 원문과 상이한 해석이 있을 수 있으며, 인용 시 반드시 원문을 확인하세요.